If you have a fragile immune system, traveling by plane might be your worst nightmare. Being in a confined space with so many strangers means you are hanging out with a lot more bacteria than you like.
Make sure to pack hand sanitizer or alcohol wipes, and wipe down your armrest, folding table, and anything else you might want to touch. You don’t know just how many people have touched it before. Or if those people even sneeze into their elbows like responsible adults.
Bring a Small Bag
If you're the kind of person who keeps everything in his/her pockets, this one's for you. Normally, good pockets will help you travel light and avoid carrying a big bag, but planes are a different story.
Since you'll be sitting down most of the time and given that your carry-on is in the overhead compartment, you probably don't feel like getting up whenever you need your wallet, bubblegum, or the USB key on your keychain. Get a little bag to fit all those items in and stick it in the pocket of the seat in front of you as you buckle up.
Plan Your Bathroom Breaks
Waiting in line for the aircraft bathroom is no fun. This is why you want to carefully plan your trips to the toilet when you can. It is less likely to have a long line to the bathroom right after takeoff (of course, only after the seatbelt sign is turned off) and before the crew starts rolling out the drink cart.
Time your visits to the potty palace, and you can do your business in peace. Just know that if you don't leave after 20 minutes, a staff member will have to knock and make sure everything is in order.
The staff is busy — mainly busy serving the dozens of other people on the plane. This means they come in contact with loads of other individuals who may have been less than sanitary.
Try being as self-sufficient as possible and bring your own snacks. This way you are the only person handling them, and you also free yourself up from the confines of the crew's service schedule.
Opt for the Smallest Bag
You are sitting in the same place for hours on end, and, at some point, no legroom in the world will be enough. You need to be smart about the way you utilize your space, and that means the personal bag you board the plane with has to be as small and as soft as possible.
Squash the bag and move it around to fit your needs — under the seat, in the pocket of the seat in front of you, or behind your lower back when it starts hurting from sitting down for too long. Versatility is key.