Ectrodactyly is famously known as “lobster claw hand” or “split hand malformation,” and we bet you can figure out why. Individuals with this disorder have a cleft where their middle toes or fingers should be, meaning they’ll only have the outermost toes or fingers, though there is some variance in how it manifests.
There are a number of ways for this disorder to appear, though it’s always through some change in chromosome seven. While the disorder will likely affect people their entire lives unless they undergo many surgeries, there are some people who have not only prospered but become famous, such as chess players, actresses, and athletes.
It's Not a Disability
Due to an extremely rare development in the womb, Wang Fang, born in China, has feet that are turned a hundred and eighty degrees on her ankles. However, she refuses to call it a disability. She can run just as fast as her friends and hold a regular job as a waitress.
Other than putting her shoes on backward, there's really nothing wrong with her. It was feared she wouldn't be able to walk properly when she was born, but it turns out she doesn't have any other side effects, which must be a one-in-a-trillion chance.
More Limbs Than Normal
For a really high percentage of people, the number of limbs is four. Two arms, two legs. That's pretty much how it goes with mammals. Polymelia, however, bucks the trend and can add more. It's a birth defect that is said to be the result of an improperly-absorbed twin.
It's often found in animals, and conjoined twins are a form of this defect, which results from an absorption that is even less complete. The additional limbs are often shrunken, deformed, and unable to be of use. It's also possible that one or more genes have gone through a mutation, resulting in an additional limb.
Gut Fermentation Syndrome
None of us like to be hungover, even if it was for a good reason. But people who have Auto-brewery syndrome, otherwise known as gut fermentation syndrome, will always be hungover. Sometimes it takes a little bit of alcohol, sometimes it takes none at all.
The syndrome occurs when your gut produces an excess of saccharomyces cerevisiae, which is a form of yeast. The yeast then sits in the GI tract, which will ferment things and produce ethanol, a form of alcohol. As you might expect, this leads to the absorption of that alcohol, and constantly being drunk or hungover.
Want More Hair? You Got It
For most people, having hair on their heads, chins, chests, and maybe legs is good enough. For people with Ambras syndrome, they're going to have much more. It can potentially cause hair all over their bodies, but each person usually has it isolated to certain places. It can, however, cover them from head to toe, which is known as hypertrichosis, or “werewolf syndrome.”
The syndrome is quite rare – it has affected only about fifty people since the Middle Ages. The responsible gene behind this one is TRPS1, a mutation that disrupts messages sent to cells developing follicles.